Indiana University and IU Health, including Riley Hospital for Children, will strategically invest in world-class research and training in selected areas of the health sciences—with emphasis on cancer, cardiovascular disease, and the neurosciences—through targeted hiring, collaboration, and infrastructure investments which have the potential to be translated into new and improved treatments, cures, and procedures. Recognizing our responsibility to take a leadership role in improving health in our state, IU will continue to invest and coordinate its efforts in public health and will seek to work with state government agencies to help address Indiana’s public health problems.
Priority Six: Health
Priority Six action items
1. IUSM, and where relevant the other IU clinical schools, will continue to build research capacity in selected areas, with special focus on research in population health management, cancer, cardiovascular disease, the neurosciences, and pediatrics through the Riley Children’s Hospital and Foundation, in order to achieve preeminence in these areas, and to generate increased external research funding from the NIH, DOD, Patient-Centered Outcomes Research Institute (PICORI), and other external sources.
- Across all U.S. medical schools, the Indiana University School of Medicine has risen in the National Institutes of Health (NIH) rankings from 41st in 2013 to 36th in 2015 to a (tentative) 33rd in 2017.
- IUSM is expected to receive at least $135 million in NIH funding in FY2017.
- $320M in funding including:
- Precision Health Grand Challenge
- Contributions to Opioid Grand Challenge
- Alzheimer’s Disease NIH $45M, 5-year grant
- NCAA—Department of Defense Grand Alliance: concussion assessment, research, and education (CARE) consortium
- Lilly Endowment: Indiana Collaborative Initiative for Talent Enrichment (INCITE).
2. IUSM will work with the clinical schools, other academic units across the university, and IU Health to recruit, mentor, and retain researchers, educators, and clinicians in these key areas, using cluster hires (see Bicentennial Priority Three) and other innovative mechanisms such as joint appointments between schools.
Recent hires include:
- David Boothman, Ph.D.
- Sid and Lois Eskenazi Chair in Cancer Research Professor, Department of Biochemistry and Molecular Biology
- Associate Director of Translational Research, IU Simon Cancer Center
- Co-Program leader, Experimental and Developmental Therapeutics Program, IU Simon Cancer Center
- Program leader, Cancer Chemical Biology, Center for Chemical and Structural Biology
- Peter Embi, M.D.
- President and CEO, Regenstrief Institute
- Associate Dean for Informatics and Health Services Research, IUSM
- Kun Huang, Ph.D.
- Director of Data Sciences and Informatics and Chair in Genomic Data Sciences, Precision Health Initiative, IU
- Assistant Dean for Data Sciences, Professor of Medicine, and Center for Computational Biology and Bioinformatics Senior Investigator, IUSM
- Senior Investigator, Regenstrief Institute
- Paul Wallach, M.D.
- Executive Vice President, Academic Affairs—Education, IU Health
- Executive Associate Dean of Educational Affairs and Continuous Improvement, IUSM
- Michael Weiss, M.D., Ph.D., M.B.A.
- Chair, Department of Biochemistry and Molecular Biology, IUSM
- Leader of Chemical Biology and Biotherapeutics, Precision Health Initiative, IU
3. IU will invest in the infrastructure to foster collaboration in research and educational programs among the clinical schools and other academic units, in order to increase opportunities for students and researchers, leveraging the Indiana Clinical and Translational Sciences Institute (CTSI) wherever possible.
Perfect “10”Score in CTSA renewal grant
- CTSA Renewal Grant—received a perfect renewal score of 10
- IU Health Values Grant restructure for greater impact
- WeCare/WeCare Plus: Focused on high priority risk factors for maternal health (smoking, mental health, obesity/nutrition) and infant health (safe sleep, breastfeeding) to reduce infant mortality rates across all races and socioeconomic status in Marion and Delaware counties. Program uses local community health workers with tailored health educational messaging. Outcomes after 18 months were very positive:
- Smoking reduction/cessation (11%)
- Substance abuse reduction/cessation (67%)
- Mental Health, PHQ-9/GAD-7 improved (38%)
- Nutrition, fewer skipped meals in last week (18%)
- Eligible persons successfully enrolled in WIC (67%)
- Safe Sleep, more sleeping alone on back (15%)
- Breastfeeding (34%)
- Other WeCare/WeCare Plus projects include:
- An IU Faculty Research Opportunities Grant funded a program that encourages physical activity for women during pregnancy and post-partum to improve physical and mental well-being and establish and sustain healthy behaviors
- ISDH Round II SafetyPIN grants are under review
- Birth spacing—evidence-based interventions that have lowered IM in Missouri
- Predictive modeling/risk stratification of women at highest risk for IM
- Grant submission in preparation for the Community-Based Addiction Reduction Program (CARE)
- CARE Plus/IU GC Opioid Initiative
- Partner with human-centered design experts to understand women’s experience of opioid addiction in the pre-and post-natal period
- Fortify existing WeCare CHW’s training in addiction recovery management, hire and train CARE addiction recovery CHW, add a Circle of Security therapist focused on mother-infant attachment
- Recruit and provide ongoing services to women with infants admitted to the NICU for treatment of NAS
- The Glycemia Reduction Approaches in Diabetes (GRADE) project is funded by the National Institute of Diabetes and Digestive and Kidney Diseases, part of NIH. Type 2 diabetes is an epidemic that threatens to become the century’s major public health problem and poses enormous human and economic challenges worldwide. Most people with diabetes need two medications to control blood glucose levels. A major challenge is to determine which drug is the best choice to combine with metformin, the most commonly used diabetes drug. GRADE will determine which combination of two medications is best for glycemic control, has the fewest side effects, and is the most beneficial for overall health.
- The Monon Trail Project is a public health initiative focused on investigations surrounding the finding that the contiguous Hamilton County and Marion County have a dramatic difference in life expectancy and other health indicators, with Hamilton being the very best and Marion being the very worst in the state.
4. IU will coordinate multiple schools, departments, campuses, medical centers, and faculty to develop new interprofessional degrees and special qualifications in the health sciences to better prepare professionals for future team-based and population-focused models of health care delivery.
- Establishment of the university-wide Center for Interprofessional Health Education to prepare students for practicing in a team care environment. The goal is to facilitate integration of IPE methodology into curricula and practice, providing students with learning opportunities that will help them excel in their professions.
- Launch of Team Education Advancing Collaboration in Healthcare (TEACH!), IU’s official curriculum for teaching and assessing the foundational collaborative practice competencies across the Fairbanks School of Public Health and the Schools of Dentistry, Health and Rehabilitation Sciences, Medicine, Nursing, Optometry, Public Health-Bloomington, and Social Work. The TEACH! framework was built upon Core Competencies for Interprofessional Collaborative Practice (Interprofessional Education Collaborative, 2016) developed by the IU Interprofessional Practice and Education Center Advisory Board to ensure that IU learners are systematically prepared to work across professions to improve health and health care outcomes through high-quality, team-based care.
- CHIIS Certificate Program in Implementation Science: The mission is to use implementation science to produce high-quality, patient-centered, and cost-effective health care delivery by using the methods and tools of implementation science and promoting innovation, ensuring that every patient receives the most personalized, valued, safest, and highest quality care.
- Anesthesia Assistant Program
5. IU will facilitate public-private and other interinstitutional partnerships to accelerate the translation of discoveries into practice.
- INCITE: $25 million gift from Lilly Endowment to foster collaboration between IUSM and non-academic partners to enhance research and education and economic health of Indiana’s life sciences:
- Recruitment of biomedical scientists
- Bioinformatics training program
- Center for Advanced Chemical and Structural Biology
- Areas of focus include genomic medicine, cancer, dementia, diabetes, childhood diseases
- LifeOmic: Public-private partnership of LifeOmic, Indiana University, and Regenstrief to allow for seamless collaboration to develop a data commons for storage of genetic and other health-related data for millions of patients within a single repository. Benefit is to researchers and clinicians around the state, to encourage discoveries and improve the delivery of personalized health care.
- Indiana Center for Biomedical Innovation (ICBI): created in 2016 with a mission to create an ecosystem for entrepreneurship, technology development, and commercialization at the IUSM campus. Goals include:
- Create facilities for technology development and entrepreneurial ecosystem
- Provide technical, business, and other mentorship to entrepreneurial faculty, postdocs, and students through the ICBI Advisory Council
- Develop funding mechanisms for technology development
- Develop networks to attract investment and leadership for startup companies from the local community and through partnership with Stanford-SPARK
6. IU will work with its clinical partners to increase integration and alignment of services, and with IU Health to address the obsolescence and over-capacity problems at University Hospital and Methodist Hospital.
- As part of enterprise alignment and joint strategic planning with IU Health, adopted an alignment strategy that serves to:
- Ensure governance alignment
- Adopt a common set of principles to guide relationship
- Articulate a shared vision and strategy
- Define performance expectations and goals for organizations and individuals
- Bridge the operating model gap
- Design an economic model that reflects strategy and enables operations
- Major strategic facility investments scheduled for 2018–26 include:
- Riley Hospital for Children Maternity and Newborn Health Tower. This project is expected to begin in 2018 and be completed in 2020.
- IU Health Bloomington medical campus: new hospital, ambulatory center, and co-located education building for IU School of Medicine and School of Nursing. This project is expected to break ground early in 2018 and be completed at the end of 2020.
- Adult hospital consolidation at the academic health center, downtown Indianapolis: a multiphased project that will take a number of years to complete. The timeline for the first phase of the work, including the ambulatory center and additional critical care beds, is currently under final development.
- New cancer center at IUH North Hospital: The two-story center will consolidate IUH cancer services in the region, as well as provide new radiation oncology services. This project is expected to start in 2018 and be completed by the end of 2019.
- Addition of in-patient beds to expand capacity at IUH West Hospital: The expansion will add 48 med/surg beds, as well as additional OR and cath lab space. This project is expected to begin in 2018 and be completed in 2020.
- Precision Health Infrastructure
- Cell therapy GMP Facility: first room is ready, second room will be operational in December 2017
- NMR: 600-MHz device purchased and will be operational by September 2018
- Cryo-EM: facility and infrastructure planning finalized, project initiation scheduled for November 2017, in partnership with Eli Lilly and Company
7. Every IU campus has important and productive relationships with many community and government partners in health care and public health across Indiana. IU will work closely with these and new partners to ensure that its undergraduate and graduate professional training programs in all of its clinical schools and on all campuses fully meet the health needs of the state. This includes leading a statewide expansion of primary care residencies and other clinical education settings.
- The expansion of graduate medical education includes:
- In 2017, 7 new resident positions added to the current 240
- Planned for 2018, 5 residents per year through the expansion at IU Health Arnett in West Lafayette (Family Medicine Center patient care began in January 2017)
- Planned for 2019, expansion of residencies in southwestern Indiana (at Vincennes, Jasper, and Evansville)